Green Tea

For those receiving ketamine therapy, maintaining bladder health is an important part of your self-care plan. One simple addition that may help is green tea, which contains the antioxidant compound EGCG (epigallocatechin gallate). EGCG has been studied for its protective effects on the bladder’s epithelial lining—the thin layer of cells that helps maintain the bladder’s barrier function and prevent irritation.

From a biological standpoint, EGCG supports bladder health through several mechanisms. It acts as a potent scavenger of free radicals, reducing oxidative stress that can damage delicate epithelial cells. It also influences inflammatory signaling pathways, particularly by downregulating NF-κB activity, a key driver of tissue inflammation. In laboratory studies, EGCG has even been shown to help preserve tight junction proteins, the structures that keep the bladder lining sealed and resilient. Together, these effects may help protect the bladder’s mucosal barrier during ketamine therapy, when inflammation or epithelial stress can sometimes occur.

Drinking one to two cups of brewed green tea daily provides gentle hydration and a natural source of antioxidants that may help reduce oxidative stress in bladder tissues. Choose decaffeinated varieties if you are sensitive to caffeine, and avoid concentrated supplements unless directed by your clinician.

As always, let your care team know about any changes to your diet or supplement use, and pair this practice with other bladder-supportive habits—adequate hydration, limiting alcohol and high-acid foods, and mindful voiding patterns—to promote long-term urinary wellness throughout your treatment.

~ Dr. Logan Marcus